a revolutionary solution until 2030

A revolutionary development in dental science could soon allow adults to regenerate their teeth, just as children do, writes the Indian Express. Researchers in Japan are preparing to test a breakthrough drug that has shown promising results in animal studies, including mice and mink.

This innovative approach focuses on a specific gene, USAG-1 (associated with uterine sensitization), which regulates tooth formation by inhibiting the development of potential tooth germs. By using an Anti-USAG 1 antibody to neutralize this gene, scientists aim to stimulate the growth of new teeth.

The initial phase of clinical trials will begin at Kyoto University and Kitano Hospital, focusing on 30 adult men between the ages of 30 and 64 who are missing at least one molar. This study will last 11 months, and future phases will include children with congenital tooth deficiencies and elderly adults.

According to Dr. Niyati Arora, successful studies could address the significant challenge faced by children with anodontia – a condition that results in missing teeth from birth – where current solutions are limited to dentures or implants.

This discovery offers hope not only for children, but also for adults who have lost teeth, as it represents a non-invasive alternative that could significantly improve the quality of life and reduce the long-term costs of dental treatments.

In addition, the research could lead to advances in regenerative medicine and the study of stem cells. Although the drug has been in development since 2005 and could take several years before it is widely available, it promises to revolutionize dental care by 2030, offering a long-awaited solution to tooth loss.